教學大綱與進度

課程基本資料：

學年期	課號	課程名稱	階段	學分	時數	修	教師	班級	人	撤	備註
112-2	331798	結晶學	1	3.0	3	★	許益瑞	高分所	8	0	限制7人分子四和高分所合開

教學大綱與進度：

教師姓名	許益瑞　教師諮商時間(Office Hours)
Email	ijuihsu@ntut.edu.tw
最後更新時間	2024-05-26 21:18:55
課程大綱	結晶學已經是成為當今科學研究領域的一門重要知識與技術。至目前為止至少有20位諾貝爾獎得主其貢獻都與結晶學有關。在這課程，我們將闡述結晶學的相關基本知識，例如: 晶格、對稱、原子散射、結構因子及解結構。此外，這門課程也將涵蓋實際操作解結構。所有基礎知識與實作，涵蓋單晶繞射與粉末繞射。也將涵蓋部分蛋白質結晶學的基本知識。 Crystallography has become an important field in scientific knowledge and technique in physics, chemistry, materials, and biology, which has been recognized by more than 20 winners of Nobel prize. In this course, we will illustrate the fundamental knowledge about crystal lattice, symmetry, atomic scattering, structure factor, and structure determination. In addition, the course also includes practices in structure determination by single crystal x-ray diffraction and powder x-ray diffraction. All fundamental knowledge and practices are mainly in small molecular cases, but part of knowledge of protein crystallography will also be included.
課程進度	1. Introduction to X-ray 2. Diffraction of X-ray 3. Crystals, Symmetry, and Space Groups 4. Intensity Data Collection and Data Reduction 5. Theory of Structure Factors and Fourier Syntheses 6. Phase Problem-Direct Methods, Patterson Methods, and Heavy Atom Methods 7. Refinement and Results 8. Modern ab initio structure determination from powder x-ray diffraction.
評量方式與標準	Midterm 30% Final 30% Homework 40%
使用教材、參考書目或其他	【遵守智慧財產權觀念，請使用正版教科書，不得使用非法影印教科書】 使用外文原文書：是 1. G. H. Stout and L. H. Jensen, X-ray Structure Determination-A practical guide, 2nd Ed.
課程諮詢管道	Tue: 3,4 and Thur : 5,6 or by appointment
課程對應SDGs指標
備註	In case the remote online lecture : using Microsoft Teams : 112-2_331798_結晶學