課 程 概 述
Course Description

課程編碼
Course Code
中文課程名稱
Course Name (Chinese)
英文課程名稱
Course Name (English)
總學分數
Credits
總時數
Hours
6805011 蛋白質工程學 Protein Engineering 3.0 3
中文概述
Chinese Description
蛋白質在眾多生物巨分子中,其結構與特性是最為複雜且重要的。蛋白質在生物系統中最重要的工作就是催化生化反應的進行,諸多天然存在或基因轉殖的蛋白質,在生物技術的應用上,有可能會遇到一些應用的瓶頸,例如活性、熱穩定性或基質專一性的限制。蛋白質工程學就是基於此,利用對蛋白序列或結構的知識,配合基因工程的技術,來改良蛋白的特性,以增進其商業上的價值。
英文概述
English Description
The structures and characteristics of proteins are the most complicated and important among many macrobiomolecules. The most important function of proteins is to catalyze bioreactions in biosystems. Many natural or transgenic proteins have some disadvantages when they are applied in biotechnology, such as the limitations of specific activity, thermostability, and substrate specificity. Protein engineering aims to improve these characteristics of proteins based on the knowledge of the amino acid sequences and structures of proteins combined with genetic engineering, leading to increase their commercial values.

備註:

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