||Manufacturing Execution System (MES) is the major information exchange portal of product records from order releasing to shipping. With real time data, MES allocates, implements, and responses to fulfill the production plans rapidly and at the same time improves the resource utilization by limiting non-value added activities. The benefit of using MES includes better performance in equipment ROI, on-time delivery, inventory turn-over rate, and hence higher revenue and cash-flow. Data collected by MES is served as the communication venue within the supply chain. This course focuses on the concept and basic functions of MES through simulation sections and practical cases.